News
Posts are organized into categories for ease of navigation:
- Algorithm - developments to the interpretation algorithm implemented in Python.
- Announcement - general news related to the Molecular Oncology Almanac.
- Database - changes and additions to the underlying knowledge base.
- Release - aggregated release notes from GitHub releases (serving as the project changelog).
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Database release
Revised entries:
- (FDA) KRAS p.G12C and sensitivity to sotorasib’s description was revised to remove underscores.
- (Preclinical) KRAS somatic variants and sensitivity to FGFR1 inhibitor + trametinib was revised to remove a trailing space from the therapy name.
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Database release
Revised entries:
- (FDA) KRAS p.G12C and sensitivity to sotorasib’s description was revised to remove underscores.
- (Preclinical) KRAS somatic variants and sensitivity to FGFR1 inhibitor + trametinib was revised to remove a trailing space from the therapy name.
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Algorithm release 0.4.2
This release utilizes the v.2021-02-04 release of the underlying MOAlmanac database.
Continue reading -
Database release
Added entries:
- (FDA) BCR-ABL1 and sensitivity to asciminib in chronic phase chronic myeloid leukemia.
- (Clinical evidence) SPOP missense somatic variants and favorable prognosis in de-novo metastatic castration-sensitive prostate cancer.
- (Clinical evidence) SPOP missense somatic variants and sensitivity to abiraterone in metastatic castration-resistant prostate cancer
- (Clinical evidence) SPOP missense somatic variants and sensitivity to anti-androgen therapy.
- (Inferential) CD274 amplification and sensitivity to atezolizumab in non-small cell lung cancer.
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Database release
Added entries:
- (FDA) EGFR exon 20 insertion variants and sensitivity to mobocertinib in non-small cell lung cancer.