News
Posts are organized into categories for ease of navigation:
- Algorithm - developments to the interpretation algorithm implemented in Python.
- Announcement - general news related to the Molecular Oncology Almanac.
- Annual newsletters - annual newsletters that recap updates.
- Database - changes and additions to the underlying knowledge base.
- Release - aggregated release notes from GitHub releases (serving as the project changelog).
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Database release
This release contains updates to the draft version of the database. EGFR TKD activating variants was introduced as a biomarker and associated with regulatory approvals from the European Medicines Agency (EMA) and Health Canada (HC). No additional genomic knowledge statements were added with this release, though several were modified.
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Database release
This release contains updates to the draft version of the database with FDA precision oncology approvals from February 2026. Specifically, indications and derived relationships were updated for Braftovi (encorafenib), Hernexeos (zongertinib), and Keytruda (pembrolizumab).
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Database release
This release contains updates to the draft version of the database with FDA precision oncology approvals for Akeega. Additionally, the Organizations table was merged into the Agents table.
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2025 newsletter
Happy holidays from the Molecular Oncology Almanac team! Thank you all for the support throughout the year. This was a huge year for development. Here, we’ll share a recap of what we have done and where we are going.
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Database release
This release contains updates to the current and draft versions of the database with FDA precision oncology approvals from October, November, and December 2025.
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